Nuevas evidencias sobre Tiotropio Respimat vs Tiotropio en Handihaler

Use of tiotropium Respimat^® was associated with an almost 30% increase of mortality compared to Handihaler^® and the association was the strongest for cardiovascular/cerebrovascular death. It is unclear whether this association is causal or due to residual confounding by COPD severity.
En ERJ

• Datos conflictivos en el estudio TIOSPIR