Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials

Conclusion Our study provided a comparative safety spectrum for each category of inhaled medications. Tiotropium Soft Mist Inhaler (Respimat) had a higher risk of mortality and should be used with caution.
En Thorax

Combinación Fluticasona_Salmeterol en EPOC . En Lancet